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Obutiinib 4

Obitinib (trade name: Yinokai) is a highly selective new BTK inhibitor independently developed by Nuo Cheng Jianhua. Obitinib has an innovative compound structure, resulting in high selectivity, reduced off-target effects, and better efficacy and safety. A registered clinical trial of orbitinib for the first-line treatment of diffuse large B- cell lymphoma (DLBCL) subtype of MCD is ongoing in China. Nuocheng Jianhua has a deep layout of DLBCL disease areas and developed a variety of drug combinations to provide more and better treatment options for this aggressive lymphoma. DLBCL is the most common form of non-Hodgkin lymphoma (NHL), accounting for 31% to 34% of NHL cases worldwide. Diffuse large B- cell lymphoma accounts for 45.8 percent of all NHLs in China. Obutiinib for the treatment of DLBCL has been included in the 2021 edition of the Chinese Society of Clinical Oncology (CSCO) Lymphoma Diagnosis and Treatment Guidelines.

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