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Recombinant Oncolytic Virus M1 for Injection

It can degrade all forms (including single-stranded, double-stranded, linear and circular) of DNA and RNA without proteolytic activity, with high specificity over a wide range of conditions.

The world's original, first-of-its-kind technology-leading oncolytic virus M1

Key words: Recombinant oncolytic virus

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  • Product Description
  • Benzonase nucleases are engineered endonucleases from Serratia marcescens. It can degrade all forms (including single-stranded, double-stranded, linear and circular) of DNA and RNA without proteolytic activity, with high specificity over a wide range of conditions. It completely digests nucleic acids into 5 '-monophosphate oligonucleotides with a length of 3-5 bases (below the hybridization limit), which is most suitable for removing nucleic acids from heavy-grade proteins and conforms to FDA's treatment procedures for nucleic acid contamination. The ability of Benzonase nucleases to rapidly hydrolyze nucleic acids makes this enzyme the best choice to reduce viscosity to reduce processing time and increase protein yield. The enzyme is used in conjunction with protein extraction reagents such as BacReady-Protein Extraction Solution and RIPA Lysis Buffer to eliminate nucleic acids in crude extracts and reduce viscosity.

VRT106 for Injection, the initial product of Veronet, has made many breakthroughs: it has obtained the orphan drug qualification for liver cancer and malignant glioma issued by the US Food and Drug Administration (FDA) in the United States, the clinical implied license of Japan Drug and Medical Device Administration (PMDA) in Japan, and the clinical implied license of China Drug Administration (NMPA) in China, clinical trials for advanced solid tumors have been conducted in Japan and China.

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